Research in the biological sciences gives students a broader appreciation for their field of study. Research is an excellent way to develop problem-solving and creative thinking skills. In the process, students benefit from increased interactions with fellow students and faculty while they gain confidence through hands-on, real-world experiences in the field and in the lab.
AU Students have the opportunity to present their findings on campus and at regional and national meetings. Meetings include the Georgia Academy of Sciences Conference, the Association of Southeastern Biologists (ASB) Meeting, the Southeastern Estuarine Research Society (SEERS) Meeting, and the Southeastern Regional Yeast Meeting (SERYM), among others. In addition, the Augusta University chapter of Phi Kappa Phi hosts an annual, campus-wide research conference where students present their findings in poster format and oral presentations to the Augusta community.
Throughout the year, the Center for Undergraduate Research and Scholarship hosts the Brown Bag Series where Augusta University students from all disciplines present their research.
The Goldstein Lab the pathogenesis and repair of diffuse white matter injury – the most common neuropathological outcome of premature birth.
Research Interests: Brain Injury / Myelin / Epigenetics /
Creativity, Discovery, Engagement
Publication |
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​ Amino acid restriction, aging, and longevity: an updateAustad, S. N., Smith, J. R. & Hoffman, J. M., 2024, In: Frontiers in Aging. 5, 1393216.Research output: Contribution to journal › Review article › peer-review |
​ The companion dog as a model for inflammaging: a cross-sectional pilot studySchmid, S. M., Hoffman, J. M., Prescott, J., Ernst, H., Promislow, D. E. L. & Creevy, K. E., 2024, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review |
​ Clippers are superior to scissors in the collection of hair for chemical analysis in companion dogs: a Dog Aging Project preliminary studyDitzler, B., Evans, J. B., Illing, K., Kaeberlein, M., Promislow, D. E. L., Brindle, E., Hoffman, J. M. & Creevy, K. E., May 2024, In: American Journal of Veterinary Research. 85, 5, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review |
​ THE BENEFITS OF A PHYSICAL THERAPY PROGRAM AMONG BREAST CANCER PATIENTS WHO HAVE UNDERGONE A MASTECTOMYAsbury, E., Bennett, H., Cannon, J. & Kindred, M., 2024, In: Journal of Cancer Rehabilitation. 7, 2, p. 80-92 13 p.Research output: Contribution to journal › Article › peer-review |
​ Absence of MMF1 disrupts heme biosynthesis by targeting Hem1pin Saccharomyces cerevisiaeWhitaker, G. H., Ernst, D. C. & Downs, D. M., Dec 2021, In: Yeast. 38, 12, p. 615-624 10 p.Research output: Contribution to journal › Article › peer-review |
​ Analysis of 2,570 responses to Dog Aging Project End of Life Survey demonstrates that euthanasia is associated with cause of death but not ageDog Aging Project Consortium, Feb 2024, In: Journal of the American Veterinary Medical Association. 262, 2, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review |
​ Gut Microbiome Transplants and Their Health Impacts across SpeciesLevine, B. H. & Hoffman, J. M., Jun 2023, In: Microorganisms. 11, 6, 1488.Research output: Contribution to journal › Review article › peer-review |
​ Lactating SKH-1 furless mice prioritize own comfort over growth of their pupsHoffman, J. M., Schmitz, B., Pfabe, J. U., Ohrnberger, S. A. & Valencak, T. G., Aug 2023, In: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 193, 4, p. 453-459 7 p.Research output: Contribution to journal › Article › peer-review |
​ Blockade of interleukin-6 trans-signaling prevents mitochondrial dysfunction and cellular senescence in retinal endothelial cellsHoffman, J. M., Robinson, R., Greenway, G., Glass, J., Budkin, S. & Sharma, S., Dec 2023, In: Experimental eye research. 237, 109721.Research output: Contribution to journal › Article › peer-review |
​ Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaquesStout, M. B., Vaughan, K. L., Isola, J. V. V., Mann, S. N., Wellman, B., Hoffman, J. M., Porter, H. L., Freeman, W. M. & Mattison, J. A., Aug 2023, In: GeroScience. 45, 4, p. 2337-2349 13 p.Research output: Contribution to journal › Article › peer-review |
​ Production of a p65fl/fl/LysMCre mouse model with dysfunctional NF-κB signaling in bone marrow-derived macrophagesKorkaya, A. K., Fischer, J., Peppers, A., Crosson, S. M., Rayamajhi, M., Miao, E. A., Baldwin, A. S. & Bradford, J. W., Nov 2023, In: Innate Immunity. 29, 8, p. 171-185 15 p.Research output: Contribution to journal › Article › peer-review |
​ Orchiectomy sensitizes cortical bone in male mice to the harmful effects of kynurenineBensreti, H., Yu, K., Alhamad, D. W., Shaver, J., Kaiser, H., Zhong, R., Whichard, W. C., Parker, E., Grater, L., Faith, H., Johnson, M., Cooley, M. A., Fulzele, S., Hill, W. D., Isales, C. M., Hamrick, M. W. & McGee-Lawrence, M. E., Aug 2023, In: Bone. 173, 116811.Research output: Contribution to journal › Article › peer-review |
​ Cyclic Nucleotides as Mediators of Acinar and Ductal FunctionAlbers, T. & Sabbatini, M. E., 2021, Cyclic Nucleotides as Mediators of Acinar and Ductal Function. PancreapediaResearch output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review |
​ Validation of a Carbohydrate Antigen-19-9 Enzyme-Linked Immunosorbent Assay Kit Using a Mouse Model of Pancreatic CancerMondal, S. & Sabbatini, M., 2021, In: The Arsenal: The Undergraduate Research Journal of Augusta University. 4, 1, p. 27-27 1 p.Research output: Contribution to journal › Article › peer-review |
​ Characterizing the NADPH Oxidase 1-Evoked Pancreatic Stellate Cell SecretomeChakraborty, A., Souravi, M., Zhi, W., Csanyi, G. & Sabbatini, M., 2021, In: The Arsenal: The Undergraduate Research Journal of Augusta University. 4, 1, p. 6-6 1 p.Research output: Contribution to journal › Article › peer-review |
​ Targeting tumor microenvironment-associated cells to reverse therapy resistancePiranlioglu, R., Bradford, J. W. & Arbab, A. S., Jan 1 2021, New Targeting in the Reversal of Resistant Glioblastomas. Elsevier, p. 115-144 30 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter |
​ Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cellsČižauskaitė, A., Šimčikas, D., Schultze, D., Kallifatidis, G., Bruns, H., Čekauskas, A., Herr, I., Baušys, A., Strupas, K. & Schemmer, P., Nov 2022, In: Oncology Reports. 48, 5, 205.Research output: Contribution to journal › Article › peer-review |
​ A longitudinal analysis of the effects of age on the blood plasma metabolome in the common marmoset, Callithrix jacchusHoffman, J. M., Tran, V. L., Wachtman, L. M., Green, C. L., Jones, D. P. & Promislow, D. E. L., Apr 1 2016, In: Experimental Gerontology. 76, p. 17-24 8 p.Research output: Contribution to journal › Article › peer-review |
​ Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperatureHariharan, R., Hoffman, J. M., Thomas, A. S., Soltow, Q. A., Jones, D. P. & Promislow, D. E. L., Dec 24 2014, In: BMC Systems Biology. 8, 1, 139.Research output: Contribution to journal › Article › peer-review |
​ Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogasterHoffman, J. M., Soltow, Q. A., Li, S., Sidik, A., Jones, D. P. & Promislow, D. E. L., Aug 2014, In: Aging Cell. 13, 4, p. 596-604 9 p.Research output: Contribution to journal › Article › peer-review |
​ Canine hyperadrenocorticism associations with signalment, selected comorbidities and mortality within North American veterinary teaching hospitalsHoffman, J. M., Lourenço, B. N., Promislow, D. E. L. & Creevy, K. E., Nov 2018, In: Journal of Small Animal Practice. 59, 11, p. 681-690 10 p.Research output: Contribution to journal › Article › peer-review |
​ Reproductive Capability Is Associated with Lifespan and Cause of Death in Companion DogsHoffman, J. M., Creevy, K. E. & Promislow, D. E. L., Apr 17 2013, In: PloS one. 8, 4, e61082.Research output: Contribution to journal › Article › peer-review |
​ The companion dog as a model for the longevity dividendCreevy, K. E., Austad, S. N., Hoffman, J. M., O’Neill, D. G. & Promislow, D. E. L., Jan 2016, In: Cold Spring Harbor perspectives in medicine. 6, 1Research output: Contribution to journal › Article › peer-review |
​ MicroRNA cargo of extracellular vesicles released by skeletal muscle fibro-adipogenic progenitor cells is significantly altered with disuse atrophy and IL-1b deficiencyParker, E., Mendhe, B., Ruan, L., Marshall, B., Zhi, W., Liu, Y., Fulzele, S., Tang, Y. L., McGee-Lawrence, M., Lee, T. J., Sharma, A. K., Johnson, M., Chen, J. & Hamrick, M. W., Aug 2022, In: Physiological Genomics. 54, 8, p. 296-304 9 p.Research output: Contribution to journal › Article › peer-review |
​ Development of a novel purification protocol to isolate and identify brain microgliaDoughty, D., Rajpurohit, S. K., Trang, A., Alptekin, A., Korkaya, A. K., Achyut, B. R., Arbab, A. S. & Bradford, J. W., Aug 2022, In: Experimental Biology and Medicine. 247, 16, p. 1433-1446 14 p.Research output: Contribution to journal › Article › peer-review |
​ Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat modelYang, L., Wu, C., Parker, E., Li, Y., Dong, Y., Tucker, L., Brann, D. W., Lin, H. W. & Zhang, Q., 2022, In: Theranostics. 12, 5, p. 2205-2231 27 p.Research output: Contribution to journal › Article › peer-review |
​ Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitroRuan, L., Mendhe, B., Parker, E., Kent, A., Isales, C. M., Hill, W. D., McGee-Lawrence, M., Fulzele, S. & Hamrick, M. W., Jan 21 2022, In: Frontiers in Physiology. 12, 742004.Research output: Contribution to journal › Article › peer-review |
​ Hindlimb Immobilization Increases IL-1β and Cdkn2a Expression in Skeletal Muscle Fibro-Adipogenic Progenitor Cells: A Link Between Senescence and Muscle Disuse AtrophyParker, E., Khayrullin, A., Kent, A., Mendhe, B., Youssef El Baradie, K. B., Yu, K., Pihkala, J., Liu, Y., McGee-Lawrence, M., Johnson, M., Chen, J. & Hamrick, M., Jan 3 2022, In: Frontiers in Cell and Developmental Biology. 9, 790437.Research output: Contribution to journal › Article › peer-review |
​ The Glucocorticoid Receptor in Osterix-Expressing Cells Regulates Bone Mass, Bone Marrow Adipose Tissue, and Systemic Metabolism in Female Mice During AgingPierce, J. L., Sharma, A. K., Roberts, R. L., Yu, K., Irsik, D. L., Choudhary, V., Dorn, J. S., Bensreti, H., Benson, R. D., Kaiser, H., Khayrullin, A., Davis, C., Wehrle, C. J., Johnson, M. H., Bollag, W. B., Hamrick, M. W., Shi, X., Isales, C. M. & McGee-Lawrence, M. E., Feb 2022, In: Journal of Bone and Mineral Research. 37, 2, p. 285-302 18 p.Research output: Contribution to journal › Article › peer-review |
​ Tachycardia evoked from insular stroke in rats is dependent on glutamatergic neurotransmission in the dorsomedial hypothalamusMarins, F. R., Limborço-Filho, M., Iddings, J. A., Xavier, C. H., Biancardi, V. C., Stern, J. E., Ramiro Diaz, J., Oppenheimer, S. M., Filosa, J. A. & Peliky Fontes, M. A., Nov 2021, In: European Journal of Neurology. 28, 11, p. 3640-3649 10 p.Research output: Contribution to journal › Article › peer-review |
​ Mitochondrial DNA Haplotype Diversity in Two Portunid Populations Found along the Georgia and South Carolina CoastsAbdulovic-Cui, A., Mannix, S., Coleman, A., White, B., Mingledolph, K. & Reichmuth, J. M., May 1 2021, In: Southeastern Naturalist. 20, 2, p. 367-376 10 p.Research output: Contribution to journal › Article › peer-review |
​ Arrb1 regulates metabolic reprogramming to promote glycolysis in stem cell-like bladder cancer cellsMamouni, K., Kim, J., Lokeshwar, B. L. & Kallifatidis, G., Apr 2 2021, In: Cancers. 13, 8, 1809.Research output: Contribution to journal › Article › peer-review |
​ Bone Morphogenetic Protein-2 Induces Non-Canonical Inflammatory and Oxidative Pathways in Human Retinal Endothelial CellsAl-Shabrawey, M., Hussein, K., Wang, F., Wan, M., Elmasry, K., Elsherbiny, N., Saleh, H., Yu, P. B., Tawfik, A. & Ibrahim, A. S., Jan 29 2021, In: Frontiers in immunology. 11, 568795.Research output: Contribution to journal › Article › peer-review |
​ Role of fibro-adipogenic progenitor cells in muscle atrophy and musculoskeletal diseasesParker, E. & Hamrick, M. W., Jun 2021, In: Current Opinion in Pharmacology. 58, p. 1-7 7 p.Research output: Contribution to journal › Review article › peer-review |
​ Targeting mitochondrial metabolism in prostate cancer with triterpenoidsMamouni, K., Kallifatidis, G. & Lokeshwar, B. L., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-15 15 p., 2466.Research output: Contribution to journal › Review article › peer-review |
​ The role of β-arrestins in regulating stem cell phenotypes in normal and tumorigenic cellsKallifatidis, G., Mamouni, K. & Lokeshwar, B. L., Dec 1 2020, In: International journal of molecular sciences. 21, 23, p. 1-16 16 p., 9310.Research output: Contribution to journal › Review article › peer-review |
​ Decreased parenchymal arteriolar tone uncouples vessel-to-neuronal communication in a mouse model of vascular cognitive impairmentKim, K. J., Diaz, J. R., Presa, J. L., Muller, P. R., Brands, M. W., Khan, M. B., Hess, D. C., Althammer, F., Stern, J. E. & Filosa, J. A., Jun 2021, In: GeroScience. 43, 3, p. 1405-1422 18 p.Research output: Contribution to journal › Article › peer-review |
​ A novel heme transporter from the energy coupling factor family is vital for group a streptococcus colonization and infectionsChatterjee, N., Cook, L. C. C., Lyles, K. V., Nguyen, H. A. T., Devlin, D. J., Thomas, L. S. & Eichenbaum, Z., Jul 1 2020, In: Journal of Bacteriology. 202, 14, e00205-20.Research output: Contribution to journal › Article › peer-review |
​ Transcriptomic analysis of streptococcus pyogenes colonizing the vaginal mucosa identifies hupy, an MtsR-regulated adhesin involved in heme utilizationCook, L. C. C., Chatterjee, N., Li, Y., Andrade, J., Federle, M. J. & Eichenbaum, Z., May 1 2019, In: mBio. 10, 3, e00848-19.Research output: Contribution to journal › Article › peer-review |
​ Extracellular matrix 1 (ECM1) regulates the actin cytoskeletal architecture of aggressive breast cancer cells in part via S100A4 and Rho-family GTPasesGómez-Contreras, P., Ramiro-Díaz, J. M., Sierra, A., Stipp, C., Domann, F. E., Weigel, R. J. & Lal, G., Jan 1 2017, In: Clinical and Experimental Metastasis. 34, 1, p. 37-49 13 p.Research output: Contribution to journal › Article › peer-review |
​ NADPH oxidase 1 mediates caerulein-induced pancreatic fibrosis in chronic pancreatitisXia, D., Halder, B., Godoy, C., Chakraborty, A., Singla, B., Thomas, E., Shuja, J. B., Kashif, H., Miller, L., Csanyi, G. & Sabbatini, M. E., Feb 1 2020, In: Free Radical Biology and Medicine. 147, p. 139-149 11 p.Research output: Contribution to journal › Article › peer-review |
​ Kynurenine signaling through the aryl hydrocarbon receptor: Implications for aging and healthspanKaiser, H., Parker, E. & Hamrick, M. W., Feb 2020, In: Experimental Gerontology. 130, 110797.Research output: Contribution to journal › Review article › peer-review |
​ Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivoPierce, J. L., Roberts, R. L., Yu, K., Kendall, R. K., Kaiser, H., Davis, C., Johnson, M. H., Hill, W. D., Isales, C. M., Bollag, W. B., Hamrick, M. W. & McGee-Lawrence, M. E., Feb 2020, In: Experimental Gerontology. 130, 110818.Research output: Contribution to journal › Article › peer-review |
​ Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatinFolk, W. P., Kumari, A., Iwasaki, T., Pyndiah, S., Johnson, J. C., Cassimere, E. K., Abdulovic-Cui, A. L. & Sakamuro, D., Apr 5 2019, In: Journal of Biological Chemistry. 294, 14, p. 5700-5719 20 p.Research output: Contribution to journal › Article › peer-review |
​ A potential role for ceramide in the regulation of mouse epidermal keratinocyte proliferation and differentiationJung, E., Griner, R. D., Mann-Blakeney, R. & Bollag, W. B., 1998, Journal of Investigative Dermatology. 4 ed. Nature Publishing Group, Vol. 110. p. 318-323 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter |
​ Augmented astrocyte microdomain Ca 2+ dynamics and parenchymal arteriole tone in angiotensin II-infused hypertensive miceDiaz, J. R., Kim, K. J., Brands, M. W. & Filosa, J. A., Mar 2019, In: Glia. 67, 3, p. 551-565 15 p.Research output: Contribution to journal › Article › peer-review |
​ Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironmentRausch, V., Liu, L., Apel, A., Rettig, T., Gladkich, J., Labsch, S., Kallifatidis, G., Kaczorowski, A., Groth, A., Gross, W., Gebhard, M. M., Schemmer, P., Werner, J., Salnikov, A. V., Zentgraf, H., Büchler, M. W. & Herr, I., Jul 2012, In: Journal of Pathology. 227, 3, p. 325-335 11 p.Research output: Contribution to journal › Article › peer-review |
​ The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferationSalazar, N., Muñoz, D., Kallifatidis, G., Singh, R. K., Jordà, M. & Lokeshwar, B. L., Aug 28 2014, In: Molecular cancer. 13, 1, 198.Research output: Contribution to journal › Article › peer-review |
​ Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signallingKallifatidis, G., Rausch, V., Baumann, B., Apel, A., Beckermann, B. M., Groth, A., Mattern, J., Li, Z., Kolb, A., Moldenhauer, G., Altevogt, P., Wirth, T., Werner, J., Schemmer, P., Büchler, M. W., Salnikov, A. V. & Herr, I., Jul 2009, In: Gut. 58, 7, p. 949-963 15 p.Research output: Contribution to journal › Article › peer-review |
​ Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancerKallifatidis, G., Hoy, J. J. & Lokeshwar, B. L., Oct 1 2016, In: Seminars in Cancer Biology. 40_41, p. 160-169 10 p.Research output: Contribution to journal › Review article › peer-review |