Graduate Program Director for Physiology
Phone: (706) 721-2180
Fax: (706) 721-7299
Email: dilatovskaya@augusta.edu
Office: CA-3137
Lab: CA-3091
Peter the Great Saint Petersburg Polytechnic University, Physics, BS, 2007
Peter the Great Saint Petersburg Polytechnic University, Physics, MS, 2009
Institute of Cytology, Russian Academy of Sciences, Cellular Biology, PhD, 2012
2021 - Associate Professor, Department of Physiology, Medical College of Georgia, Augusta University
2017-2021 - Assistant Professor, Medical University of South Carolina
2015-2017 - Assistant Professor, Medical College of Wisconsin
Research interests: water and electrolyte homeostasis, mitochondrial bioenergetics, regulation of ion channel function and their role in the development of cardiorenal pathologies, such as hypertension and polycystic kidney disease, and sex-related differences in these conditions.
Dr. Daria Ilatovskaya joined the Department of Physiology at the Medical College of Georgia at the Augusta Univeristy in July 2021, where she moved from the Medical University of South Carolina in Charleston. Dr. Ilatovskaya is an ion channel biophysicist and physiologist by training, she obtained her PhD degree at the Institute of Cytology in St. Petersburg, Russia, and spent her early career years at the Medical College of Wisconsin. Dr. Ilatovskaya studies cardiorenal function, and especially blood pressure control, which is a highly clinically relevant problem. The number of people living with high blood pressure is predicted to be 1.56 billion worldwide by the year 2025. Dr. Ilatovskaya’s research is aimed at advancing our understanding of the mechanisms that underlie kidney and heart disease. The laboratory specializes in investigating the regulation of ion channels and transporters in the different aspects of cardiorenal disorders. Recently, the scope of the lab has been expanded towards the studies of cardiorenal mitochondrial bioenergetics, with a focus on sex differences in pathobiology.
Methods: The lab uses in vivo, ex vivo and in vitro techniques to study physiology using an integrative approach that includes the molecular, cellular, and whole-organism levels. In addition to routine molecular biology, the lab specializes in unique methods, such as single-channel electrophysiology performed on freshly isolated nephron segments and mitochondria, the state-of-the-art in vivo and ex vivo confocal and epifluorescence microscopy, measurements of mitochondrial bioenergetics, chronic blood pressure monitoring and other sophisticated techniques.
Core lab values: solid science, success of our trainees, diversity and inclusion, outreach/advocacy/volunteering, and life balance (last but not least) are the staples at the core of Dr. Ilatovskaya's lab philosophy.
2022- Selected for the inaugural council on Undergraduate Research(CUR) Students Transforming
Through Research(STR) program for undergraduate research advocacy.
2020- Journal of the American Society of Nephrology Editorial Fellow.
2019 - Lazaro J Mandel Young Investigator Award, the American Physiological Society.
2019 - New Investigator Award, Renal Section of the American Physiological Society.
2018 - FAHA distinction from the American Heart Association.
2018 - Outstanding research presentation winner, Junior Faculty - Basic Research category,
Medical University of South Carolina.
2017 - Best Poster Award winner in the Junior Faculty - Basic Research category, Medical
College of Wisconsin Research Day.
2016 - Research Recognition Award for junior faculty (Renal Section of the American Physiological
Society) at Experimental Biology Meeting.
2014 - Edward J. Lennon, MD Award for an Outstanding Woman Postdoctoral Researcher.
Representative Publications
Mamenko M, Lysikova DV, Spires DR, Tarima S, Ilatovskaya DV. Practical notes on popular statistical tests in renal physiology. (2022) Am J Physiol Renal Physiol. 323(4):F389-F400. PMID: 35834273 |
Ilatovskaya DV#, Levchenko V, Winsor K, Blass GR, Spires DR, Sarsenova E, Polina I, Zietara A, Paterson M, Kriegel A, Staruschenko A. Effects of Elevation of ANP and Its Deficiency on Cardiorenal Function. (2022) JCI Insight. 2022;7(9):e148682. PMID: 35380994 #Corresponding author |
Sudarikova AV, Fomin MV, Sultanova RF, Domondon M, Zhao Y, Perez S, Shamatova M, Lysikova DV, Spires DS, Ilatovskaya DV. Functional role of histamine receptors in the renal cortical collecting duct cells. (2022) Am J Physiol Cell Physiol. 322(4): C775-C786. PMID: 35081320 |
Sudarikova AV, Vasileva VY, Sultanova RF, Ilatovskaya DV. Recent Advances in Understanding Ion Transport Mechanisms in PKD. Invited review. (2021). Clinical Science. 135(21):2521-2540. PMID: 34751394. |
Polina I, Spicer MJ, Domondon M, Schibalski RS, Sultanova RF, and Ilatovskaya DV. Inhibition of neprilysin with sacubitril without RAS blockage aggravates renal disease in Dahl SS rats. (2021) Renal Failure 43(1):315-324 PMID: 33541194 |
Sultanova RF, Schibalski RS, Yankelevich IA, Ilatovskaya DV. Sex differences in renal mitochondrial function: a hormone-gous opportunity for research. (2020). Am J Physiol Renal Physiol. 319(6):F1117-F1124 PMID: 33135479 |
Polina I, Domondon M, Fox R, Sudarikova A, Troncoso M, Vasileva V, Kashyrina Y, Gooz M, Schibalski R, DeLeon-Pennell KY, Fitzgibbon WR, Ilatovskaya DV. The differential effects of low dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension. (2020) Am J Physiol Renal Physiol. 319(1):F63-F75. PMID: 32463726. Featured in APSselect collection, August 2020 |
Domondon M, Polina I, Nikiforova A, Sultanova R, Kruger C, Vasileva V, Fomin MV, Beeson GC, Nieminen AL, Smythe N, Maldonado EN, Stadler K, Ilatovskaya DV. Renal glomerular mitochondria function in salt-sensitive hypertension. (2020) Front Physiol. 10:1588. PMID: 32116733 PMCID: PMC7010849 |
McCrimmon A, Domondon M, Sultanova RS, Ilatovskaya DV, Stadler K. Rapid assessment of mitochondrial respiratory function in freshly isolated nephron segments. (2020). Am J Physiol Renal Physiol. 318(5):F1237-F1245 PMID: 32223308 |
Domondon M, Nikiforova AB, DeLeon-Pennell KY, Ilatovskaya DV. Regulation of mitochondria function by natriuretic peptides. (2019) Am J Physiol Renal Physiol. 317(5): F1164-F1168. PMID: 31509010. |
Dr. Ilatovskaya's Faculty Profile
Denisha Spires, PhD Postdoctoral Fellow |
Adam Jones Graduate Student
|
Alena Cherezova Senior Research Assistant |
Maksim Diakov Undergrad Student Tech
|
Ryan Schibalski |
Zeke Balbino Undergrad Student
|
Ilatovskaya Lab, 2023