Rheumatology Research

The mission of the Medical College of Georgia at Augusta University’s Division of Rheumatology is to pursue research that will directly benefit patient care for rheumatic diseases and to educate future rheumatologists in this endeavor.

Go to: Current Research Funding | Current Clinical Trials | Recent Faculty Publications | Recent Fellow Publications

Current Research Projects

Senile and Postmenopausal Osteoporosis
Osteoporosis in Special Populations:
- Rheumatoid Arthritis
- Spinal Cord Injuries and Disorders
Systemic Lupus Erythematosus and Cardiovascular Disease
Health Care Disparities in Rheumatic Diseases
Rheum2Learn 2.0 Study

Current Research Funding

Principal Investigator: Laura Carbone, MD
Title: Development of a Novel Soluble Epoxide Hydrolase Inhibitor as a Strategy for Treating Neuropathic Pain in Patients with Spinal Cord Injury
Source of Funding: Department of Defense
Funding Period: 9/30/2021-9/29/2025

Principal Investigator: Laura Carbone, MD
Title: FY2024 Rheumatology Foundation Fellowship Training Award for Workforce Expansion
Source of Funding: Rheumatology Research Foundation
Funding Period: 7/1/2024-6/30/2026

Principal Investigator: Laura Carbone, MD
Title: Calculator for Length of Use of Bisphosphonates (CLUB)
Source of Funding: NIH R09
Funding Period: 9/15/2022-6/30/2027

Principal Investigator: Rachel Elam, MD
Title: Fracture Risk Assessment in Persons with Rheumatoid Arthritis
Source of Funding: Rheumatology Research Foundation Scientist Development Award
Funding Period: 07/01/2023 - 06/30/2025

Principal Investigator: Hong Shi, MD
Title: Perivascular Adipose tissue in the pathogenesis of lupus vasculopathy
Source of Funding: NIH K08
Funding Period: I 01/2024-12/2028

Principal Investigator: Laura Carbone, MD
Title: FY2024 Fellowship Training Award for Workforce Expansion
Source of Funding: Rheumatology Research Foundation
Funding Period: I 07/23 - 06/24

Current Clinical Trials

A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group, 2-Arm, Multicenter, Operationally Seamless Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Efgartigimod PH20 SC in Participants Aged 18 Years and Older With Active Idiopathic Inflammatory Myopathy

Sponsor: Argenx
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 1/5/224 - 1/4/2027

PARTUS: Psoriatic Arthritis Real-World Study in the US (I1F-MC-B019)

Sponsor: Eli Lilly
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 12/10/2023 - 12/9/2025

A Phase IIa, Randomized, Parallel, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Enpatoran in Dermatomyositis and Polymyositis Participants receiving Standard of Care

Sponsor: EMD Serono, Inc./Merck Serono S.A.
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 12/7/2023 - 12/6/2024

A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered GLPG3667 Once Daily for 24 Weeks in Adult Subjects With Dermatomyositis

Sponsor: Galapagos NV
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 8/1/2023 - 7/31/2025

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Obexelimab in Patients with IgG4-Related Disease (INDIGO)

Sponsor: Zenas BioPharma
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 7/26/2023 -12/31/2027

Vagus Nerve Stimulation Using the SetPoint System for Moderate to Severe Rheumatoid Arthritis: The RESET-RA Study

Sponsor: SetPoint Medical, Inc
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 7/19/2023 - 7/18/2027

1366-0031: A Phase II, randomised, placebo-controlled, double-blind, parallel-group, efficacy and safety study of at least 48 weeks of oral BI 685509 treatment in adults with early progressive diffuse cutaneous systemic sclerosis

Sponsor: Boehringer Ingelheim
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 5/4/2023 - 12/31/2026

SPIREA: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Nipocalimab in Participants with Active Idiopathic Inflammatory Myopathies

Sponsor: Janssen Research & Development, L.L.C./Janssen Pharmaceutical Products, LP/J&J
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 4/3/2023 - 12/31/2025

PVT-2201-301: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Oral Brepocitinib in Adults with Dermatomyositis

Sponsor: Priovant Therapeutics, Inc.
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 2/28/2023 - 2/27/2025

A randomized, double-blind, placebo controlled, 3-arm multicenter phase 3 study to assess the efficacy and safety of ianalumab in patients with active Sjogren's syndrome (NEPTUNUS-2)

Sponsor: Novartis
Principal Investigator: Elena Schiopu
Institution: Augusta University/MCG-Med-Rheumatology
Period: 12/12/2022 - 10/29/2029

Recent Faculty Publications

Note: Only publications in the past two years have been listed. Last updated: 7/12/2024 by Carvonne Hall

Laura Carbone, MD

Carbone L, Buzkova P, Robbins JA, Fink HA, Barzilay JI, Elam RE, Isales C. Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study. Arch Osteoporos. 2024;19(1):51. Epub 20240620. doi: 10.1007/s11657-024-01408-0. PubMed PMID: 38898169. FULL TEXT
Austin TR, Nethander M, Fink HA, Tornqvist AE, Jalal DI, Buzkova P, Barzilay JI, Carbone L, Gabrielsen ME, Grahnemo L, Lu T, Hveem K, Jonasson C, Kizer JR, Langhammer A, Mukamal KJ, Gerszten RE, Psaty BM, Robbins JA, Sun YV, Skogholt AH, Kanis JA, Johansson H, Asvold BO, Valderrabano RJ, Zheng J, Richards JB, Coward E, Ohlsson C. A plasma protein-based risk score to predict hip fractures. Nat Aging. 2024. Epub 20240527. doi: 10.1038/s43587-024-00639-7. PubMed PMID: 38802582. FULL TEXT
Austin TR, Fink HA, Jalal DI, Tornqvist AE, Buzkova P, Barzilay JI, Lu T, Carbone L, Gabrielsen ME, Grahnemo L, Hveem K, Jonasson C, Kizer JR, Langhammer A, Mukamal KJ, Gerszten RE, Nethander M, Psaty BM, Robbins JA, Sun YV, Skogholt AH, Asvold BO, Valderrabano RJ, Zheng J, Richards JB, Coward E, Ohlsson C. Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures. J Bone Miner Res. 2024. Epub 20240104. doi: 10.1093/jbmr/zjad011. PubMed PMID: 38477735. FULL TEXT
Le, Brian; Xu, Hongyan; Weaver, Frances; Huo, Zhiping; Avidano, Ryan; Hurlburt, Piper; Morgan, Sarah; Carbone, Laura. Association of Calcium and Vitamin D Supplements with Fractures in Persons with a Traumatic SCI. Topics in Spinal Cord Injury Rehabilitation. 2023. PMID: 31958428 FULL TEXT
Carbone, L.; Bůžková, P.; Fink, H.A.; Robbins, J.A.; Barzilay, J.I.; Elam, R.E.; Isales, C.; Connelly, M.A.; Mukamal, K.J. Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures and Bone Mineral Density of the Hip and Spine. The Journal of Clinical Endocrinology & Metabolism 2023, doi:10.1210/clinem/dgad275. PMID: 37200158 FULL TEXT
Carbone L, Buzkova P, Fink HA, Robbins JA, Barzilay JI, Elam RE, Isales C. The Association of Tryptophan and Its Metabolites With Incident Hip Fractures, Mortality, and Prevalent Frailty in Older Adults: The Cardiovascular Health Study. JBMR Plus. 2023;7(10):e10801. Epub 20230818. doi: 10.1002/jbm4.10801. PubMed PMID: 37808397; PMCID: PMC10556266 FULL TEXT
Elam RE, Bůžková P, Delaney JAC, Fink HA, Barzilay J, Carbone LD, Saha R, Robbins JA, Mukamal KJ, Valderrábano RJ, Psaty BM, Tracy RP, Olson NC, Huber SA, Doyle MF, Landay AL and Cauley JA. Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study. (Aug 2023). Calcified Tissue International. PMID: 37650930 FULL TEXT
Craven BC, Cirnigliaro CM, Carbone LD, Tsang P, Morse LR. The pathophysiology, identification and management of fracture risk, sublesional osteoporosis and fracture among adults with SCI. Journal of Personalized Medicine Jun 2023. PMID: 37373955 FULL TEXT
Robbins JA, Buzkova P, Barzilay JI, Cauley JA, Fink HA, Carbone LD, Chen Z, Stein PK, Elam RE, Jalal D, Sheets K, and Mukamal K. Mortality following hip fracture in older adults with and without coronary heart disease. Am J Med. (2023 Apr 24);S0002-9343(23)00244-9. Doi: 10.1016/j.amjmed.2023.03.036. Epub ahead of print. PMID: 37100188 FULL TEXT
Le B, Gonzalez B, Weaver F, Sinnott B, Ray C, Chu E, Premji S, Raiford M, Mayur O, Carbone L. Malunions following lower extremity fractures in veterans with a spinal cord injury/disorder. J Spinal Cord Med. 2024;47(2):293-9. Epub 20230328. doi: 10.1080/10790268.2023.2188391. PubMed PMID: 36977321; PMCID: PMC10885743. FULL TEXT
Shi H, Goo B, Kim D, Kress TC, Ogbi M, Mintz J, Wu H, Belin de Chantemèle EJ, Stepp D, Long X, Guha A, Lee R, Carbone L, Annex BH, Hui DY, Kim HW, Weintraub NL. Perivascular adipose tissue promotes vascular dysfunction in murine lupus. Front Immunol. 2023 Mar 16;14:1095034. doi: 10.3389/fimmu.2023.1095034. PMID: 37006244; PMCID: PMC10062185. FULL TEXT
Mohanty N, San T, Bell S, Jalla R, Williams J, Fordjour I, Siddiquee N, Gavrilova-Jordan L, Carbone L, Elam R. Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report. Case Rep Womens Health. 2023;37:e00498. Epub 20230315. doi: 10.1016/j.crwh.2023.e00498. PubMed PMID: 36968550; PMCID: PMC10034382. FULL TEXT
Barzilay JI, Buzkova P, Fink HA, Cauley JA, Carbone L, Elam R, Robbins JA, Stein P, Sheets K, Jalal D, Mukamal KJ. The associations of markers of endothelial dysfunction with hip fracture risk. Arch Osteoporos. (2023 Mar 2);18(1):39. doi: 10.1007/s11657-023-01226-w. PMID: 36859726. FULL TEXT
Elam RE, Ray CE, Miskevics S, Weaver FM, Gonzalez B, Obremskey, W, Carbone LD. Predictors of lower extremity fracture-related amputation in persons with traumatic spinal cord injury: a case-control study. Spinal Cord. (2023 Feb 16). doi: 10.1038/s41393-023-00879-1. Epub ahead of print. PMID: 36797477. FULL TEXT
Rice C, Ayyala DN, Shi H, Madera-Acosta A, Bell S, Qureshi A, Carbone LD, Coughlin SS, Elam RE. Sex and Racial Differences in Systemic Lupus Erythematosus Among US Adults in the All of Us Research Program. Arthritis Care Res (Hoboken). 2023;75(10):2096-106. Epub 20230412. doi: 10.1002/acr.25093. PubMed PMID: 36705447; PMCID: PMC10372192. FULL TEXT
Gao H, Patel S, Fohtung RB, Cawthon PM, Newman AB, Cauley JA, Carbone L, Chaves PHM, Stein PK, Civitelli R, Kizer JR. Sex- and race-specific associations of bone mineral density with incident heart failure and its subtypes in older adults. J Am Geriatr Soc. 2023 Mar;71(3):742-755. doi: 10.1111/jgs.18121. Epub 2022 Nov 5. PMID: 36334030; PMCID: PMC10023291. FULL TEXT
Sheets KM, Bůžková P, Chen Z, Carbone LD, Cauley JA, Barzilay JI, Starks JL, Miller LM, Fink HA. Association of covert brain infarcts and white matter hyperintensities with risk of hip fracture in older adults: the Cardiovascular Health Study. Osteoporos Int 2023 Jan;34(1):91-99.DOI: 10.1007/s00198-022-06565-x PMID: 36355067. FULL TEXT
Carbone LD, Ahn J, Adler RA, Cervinka T, Craven C, Geerts W, Hsu JR, Huang D, Karunakar MA, Kiratli BJ, Krause PC, Morse LR, Mirick Mueller GE, Nana A, Rogers E, Rivera JC, Spitler C, Weaver FM, Obremskey W. Acute Lower Extremity Fracture Management in Chronic Spinal Cord Injury: 2022 Delphi Consensus Recommendations. JB JS Open Access. 2022;7(4). Epub 20221208. doi: 10.2106/JBJS.OA.21.00152. PubMed PMID: 36518619; PMCID: PMC9742097. FULL TEXT
Barzilay JI, Buzkova P, Kuller LH, Cauley JA, Fink HA, Sheets K, Robbins JA, Carbone LD, Elam RE, Mukamal KJ. The Association of Lipids and Lipoproteins with Hip Fracture Risk: The Cardiovascular Health Study. Am J Med. 2022;135(9):1101-8 e1. Epub 20220606. doi: 10.1016/j.amjmed.2022.05.024. PubMed PMID: 35679877; PMCID: PMC9536862. FULL TEXT
Elam RE, Buzkova P, Barzilay JI, Wang Z, Nemet I, Budoff MJ, Cauley JA, Fink HA, Lee Y, Robbins JA, Wang M, Hazen SL, Mozaffarian D, Carbone LD. Trimethylamine N-oxide and hip fracture and bone mineral density in older adults: The cardiovascular health study. Bone. 2022;161:116431. Epub 20220513. doi: 10.1016/j.bone.2022.116431. PubMed PMID: 35577327; PMCID: PMC10712255. FULL TEXT

Hong Shi, MD

Veerapaneni P, Goo B, Ahmadieh S, Shi H, Kim DS, Ogbi M, Cave S, Chouhaita R, Cyriac N, Fulton DJ, Verin AD, Chen W, Lei Y, Lu XY, Kim HW, Weintraub NL. Transgenic Overexpression of HDAC9 Promotes Adipocyte Hypertrophy, Insulin Resistance and Hepatic Steatosis in Aging Mice. Biomolecules. 2024;14(4). Epub 20240418. doi: 10.3390/biom14040494. PubMed PMID: 38672510; PMCID: PMC11048560. FULL TEXT
Ahmadieh S, Goo B, Zarzour A, Kim D, Shi H, Veerapaneni P, Chouhaita R, Yiew NKH, Dominguez Gonzalez C, Chakravartty A, Pennoyer J, Hassan N, Benson TW, Ogbi M, Fulton DJ, Lee R, Rice RD, Hilton LR, Lei Y, Lu XY, Chen W, Kim HW, Weintraub NL. Impact of housing temperature on adipose tissue HDAC9 expression and adipogenic differentiation in high fat-fed mice. Obesity (Silver Spring). 2024;32(1):107-19. Epub 20231023. doi: 10.1002/oby.23924. PubMed PMID: 37869960; PMCID: PMC10840750. FULL TEXT
Shi H, Goo B, Kim D, Kress TC, Ogbi M, Mintz J, Wu H, Belin de Chantemèle EJ, Stepp D, Long X, Guha A, Lee R, Carbone L, Annex BH, Hui DY, Kim HW, Weintraub NL. Perivascular adipose tissue promotes vascular dysfunction in murine lupus. Front Immunol. 2023 Mar 16;14:1095034. doi: 10.3389/fimmu.2023.1095034. PMID: 37006244; PMCID: PMC10062185. FULL TEXT
Rice C, Ayyala DN, Shi H, Madera-Acosta A, Bell S, Qureshi A, Carbone LD, Coughlin SS, Elam RE. Sex and Racial Differences in Systemic Lupus Erythematosus Among US Adults in the All of Us Research Program. Arthritis Care Res (Hoboken). 2023;75(10):2096-106. Epub 20230412. doi: 10.1002/acr.25093. PubMed PMID: 36705447; PMCID: PMC10372192.
FULL TEXT

Rachel Elam, MD

Carbone L, Buzkova P, Robbins JA, Fink HA, Barzilay JI, Elam RE, Isales C. Association of serum levels of phenylalanine and tyrosine with hip fractures and frailty in older adults: The cardiovascular health study. Arch Osteoporos. 2024;19(1):51. Epub 20240620. doi: 10.1007/s11657-024-01408-0. PubMed PMID: 38898169.. FULL TEXT
Elam RE, Buzkova P, Delaney JAC, Fink HA, Barzilay JI, Carbone LD, Saha R, Robbins JA, Mukamal KJ, Valderrabano RJ, Psaty BM, Tracy RP, Olson NC, Huber SA, Doyle MF, Landay AL, Cauley JA. Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study. Calcif Tissue Int. 2023;113(6):581-90. Epub 20230831. doi: 10.1007/s00223-023-01126-8. PubMed PMID: 37650930; PMCID: PMC11229516. FULL TEXT
Carbone L, Buzkova P, Fink HA, Robbins JA, Barzilay JI, Elam RE, Isales C. The Association of Tryptophan and Its Metabolites With Incident Hip Fractures, Mortality, and Prevalent Frailty in Older Adults: The Cardiovascular Health Study. JBMR Plus. 2023;7(10):e10801. Epub 20230818. doi: 10.1002/jbm4.10801. PubMed PMID: 37808397; PMCID: PMC10556266. FULL TEXT
Carbone L, Buzkova P, Fink HA, Robbins JA, Barzilay JI, Elam RE, Isales C, Connelly MA, Mukamal KJ. Plasma Levels of Branched Chain Amino Acids, Incident Hip Fractures, and Bone Mineral Density of the Hip and Spine. J Clin Endocrinol Metab. 2023;108(11):e1358-e64. doi: 10.1210/clinem/dgad275. PubMed PMID: 37200158; PMCID: PMC11009785. FULL TEXT
Robbins JA, Buzkova P, Barzilay JI, Cauley JA, Fink HA, Carbone LD, Chen Z, Stein PK, Elam R, Sheets K, Mukamal KJ. Mortality Following Hip Fracture in Older Adults With and Without Coronary Heart Disease. Am J Med. 2023;136(8):789-95 e2. Epub 20230424. doi: 10.1016/j.amjmed.2023.03.036. PubMed PMID: 37100188; PMCID: PMC10524655. FULL TEXT
Mohanty N, San T, Bell S, Jalla R, Williams J, Fordjour I, Siddiquee N, Gavrilova-Jordan L, Carbone L, Elam R. Initial presentation of granulomatosis with polyangiitis as urethral mass mimicking urethral cancer: A case report. Case Rep Womens Health. 2023;37:e00498. Epub 20230315. doi: 10.1016/j.crwh.2023.e00498. PubMed PMID: 36968550; PMCID: PMC10034382. FULL TEXT
Barzilay JI, Buzkova P, Fink HA, Cauley JA, Carbone L, Elam R, Robbins JA, Stein P, Sheets K, Jalal D, Mukamal KJ. The associations of markers of endothelial dysfunction with hip fracture risk. Arch Osteoporos. 2023;18(1):39. Epub 20230302. doi: 10.1007/s11657-023-01226-w. PubMed PMID: 36859726; PMCID: PMC10580991. FULL TEXT
Bucur P, Weber M, Agrawal R, Madera-Acosta AI, Elam RE. Pulmonary-Renal Syndrome from Levamisole-Adulterated Cocaine-Induced Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Systematic Review. Pharmaceuticals (Basel). 2023;16(6). Epub 20230606. doi: 10.3390/ph16060846. PubMed PMID: 37375793; PMCID: PMC10301056. FULL TEXT
Elam RE, Ray CE, Miskevics S, Weaver FM, Gonzalez B, Obremskey W, Carbone LD. Predictors of lower extremity fracture-related amputation in persons with traumatic spinal cord injury: a case-control study. Spinal Cord. 2023;61(4):260-8. Epub 20230216. doi: 10.1038/s41393-023-00879-1. PubMed PMID: 36797477. FULL TEXT
Rice C, Ayyala DN, Shi H, Madera-Acosta A, Bell S, Qureshi A, Carbone LD, Coughlin SS, Elam RE. Sex and Racial Differences in Systemic Lupus Erythematosus Among US Adults in the All of Us Research Program. Arthritis Care Res (Hoboken). 2023;75(10):2096-106. Epub 20230412. doi: 10.1002/acr.25093. PubMed PMID: 36705447; PMCID: PMC10372192. FULL TEXT
Barzilay JI, Buzkova P, Kuller LH, Cauley JA, Fink HA, Sheets K, Robbins JA, Carbone LD, Elam RE, Mukamal KJ. The Association of Lipids and Lipoproteins with Hip Fracture Risk: The Cardiovascular Health Study. Am J Med. 2022;135(9):1101-8 e1. Epub 20220606. doi: 10.1016/j.amjmed.2022.05.024. PubMed PMID: 35679877; PMCID: PMC9536862. FULL TEXT
Elam RE, Buzkova P, Barzilay JI, Wang Z, Nemet I, Budoff MJ, Cauley JA, Fink HA, Lee Y, Robbins JA, Wang M, Hazen SL, Mozaffarian D, Carbone LD. Trimethylamine N-oxide and hip fracture and bone mineral density in older adults: The cardiovascular health study. Bone. 2022;161:116431. Epub 20220513. doi: 10.1016/j.bone.2022.116431. PubMed PMID: 35577327; PMCID: PMC10712255. FULL TEXT
Elam RE, Arora V, Oliver AM. (May 2022) Close, but no cigar: A case report of cannabis arteritis from smoking blunts. The Rheumatologist. pp. 43-44. www.the-rheumatologist.org
Elam R, Doan J, Weaver F, Ray C, Miskevics S, Gonzalez B, Obremskey W, Carbone L. "Pathological" fractures in spinal cord injuries and disorders: Insight into International classification of diseases, ninth revision coding. J Spinal Cord Med. 2023;46(2):317-25. Epub 20220307. doi: 10.1080/10790268.2022.2042658. PubMed PMID: 35254231; PMCID: PMC9987728. FULL TEXT
Sinnott B, Ray C, Weaver F, Gonzalez B, Chu E, Premji S, Raiford M, Elam R, Miskevics S, Parada S, Carbone L. Risk Factors and Consequences of Lower Extremity Fracture Nonunions in Veterans With Spinal Cord Injury. JBMR Plus. 2022;6(3):e10595. Epub 20220105. doi: 10.1002/jbm4.10595. PubMed PMID: 35309860; PMCID: PMC8914149. FULL TEXT

Noelle A. Rolle, MBBS, FACR, FACP

ACR Fellows-in-Training Subcommittee, Saygin D, Lin J, Rolle NA, Mamut M. Report of the American College of Rheumatology Fellows-in-Training Subcommittee: experiences of rheumatology fellows early in the COVID-19 pandemic. Arthritis Rheumatol. 2022 Aug;74(8):1457-1458. doi: 10.1002/art.42135. Epub 2022 Jun 27. PMID: 35373922; PMCID: PMC9082478.

Elena Schiopu, MD

Ritchlin CT, Mease PJ, Boehncke WH, Tesser J, Chakravarty SD, Rampakakis E, Shawi M, Schiopu E, Merola JF, McInnes IB, Deodhar A. Durable control of psoriatic arthritis with guselkumab across domains and patient characteristics: post hoc analysis of a phase 3 study. Clin Rheumatol. 2024 Jun 7. doi: 10.1007/s10067-024-06991-8. Epub ahead of print. PMID: 38844682. FULL TEXT
Khanna D, Kramer F, Höfler J, Ghadessi M, Sandner P, Allanore Y, Denton CP, Kuwana M, Matucci-Cerinic M, Pope JE, Atsumi T, Bečvář R, Czirják L, De Langhe E, Hachulla E, Ishii T, Ishikawa O, Johnson SR, Riccieri V, Schiopu E, Silver RM, Smith V, Stagnaro C, Steen V, Stevens W, Szücs G, Truchetet ME, Wosnitza M, Distler O. Biomarker analysis from the phase 2b randomized placebo-controlled trial of riociguat in early diffuse cutaneous systemic sclerosis. Rheumatology (Oxford). 2024 Mar 9:keae150. doi: 10.1093/rheumatology/keae150. Epub ahead of print. PMID: 38460548. FULL TEXT
Distler O, Allanore Y, Denton CP, Kuwana M, Matucci-Cerinic M, Pope JE, Atsumi T, Bečvář R, Czirják L, Hachulla E, Ishii T, Ishikawa O, Johnson SR, De Langhe E, Stagnaro C, Riccieri V, Schiopu E, Silver RM, Smith V, Steen V, Stevens W, Szücs G, Truchetet ME, Wosnitza M, Laapas K, Kramer F, Khanna D. Riociguat in patients with early diffuse cutaneous systemic sclerosis (RISE-SSc): open-label, long-term extension of a phase 2b, randomised, placebo-controlled trial. Lancet Rheumatol. 2023 Nov;5(11):e660-e669. doi: 10.1016/S2665-9913(23)00238-2. PMID: 38251533. FULL TEXT
Ritchlin CT, Mease PJ, Boehncke WH, Tesser J, Schiopu E, Chakravarty SD, Kollmeier AP, Xu XL, Shawi M, Jiang Y, Sheng S, Wang Y, Xu S, Merola JF, McInnes IB, Deodhar A. Sustained and improved guselkumab response in patients with active psoriatic arthritis regardless of baseline demographic and disease characteristics: pooled results through week 52 of two phase III, randomised, placebo-controlled studies. RMD Open. 2022;8(1). doi: 10.1136/rmdopen-2022-002195. PubMed PMID: 35296534; PMCID: PMC8928386. FULL TEXT
Jo J, Mills D, Dentinger A, Chamberland D, Abdulaziz NM, Wang X, Schiopu E, Gandikota G. Photoacoustic Imaging of COVID-19 Vaccine Site Inflammation of Autoimmune Disease Patients. Sensors (Basel). 2023;23(5). Epub 20230303. doi: 10.3390/s23052789. PubMed PMID: 36904999; PMCID: PMC10006996. FULL TEXT
Shen C, Risk M, Schiopu E, Hayek SS, Xie T, Holevinski L, Akin C, Freed G, Zhao L. Efficacy of COVID-19 vaccines in patients taking immunosuppressants. Ann Rheum Dis. 2022;81(6):875-80. Epub 20220223. doi: 10.1136/annrheumdis-2021-222045. PubMed PMID: 35197265; PMCID: PMC9422955. FULL TEXT
Chen X, Affinati AH, Lee Y, Turcu AF, Henry NL, Schiopu E, Qin A, Othus M, Clauw D, Ramnath N, Zhao L. Immune Checkpoint Inhibitors and Risk of Type 1 Diabetes. Diabetes Care. 2022;45(5):1170-6. doi: 10.2337/dc21-2213. PubMed PMID: 35238899; PMCID: PMC9174959. FULL TEXT
Risk M, Shen C, Hayek SS, Holevinski L, Schiopu E, Freed G, Akin C, Zhao L. Comparative Effectiveness of Coronavirus Disease 2019 (COVID-19) Vaccines Against the Delta Variant. Clin Infect Dis. 2022;75(1):e623-e9. doi: 10.1093/cid/ciac106. PubMed PMID: 35137006; PMCID: PMC9047165. FULL TEXT
Ma VT, Lao CD, Fecher LA, Schiopu E. Successful use of secukinumab in two melanoma patients with immune checkpoint inhibitor-induced inflammatory arthropathy. Immunotherapy. 2022;14(8):593-8. Epub 20220413. doi: 10.2217/imt-2021-0274. PubMed PMID: 35416067; PMCID: PMC9096604. FULL TEXT
Ritchlin CT, Mease PJ, Boehncke WH, Tesser J, Schiopu E, Chakravarty SD, Kollmeier AP, Xu XL, Shawi M, Jiang Y, Sheng S, Wang Y, Xu S, Merola JF, McInnes IB, Deodhar A. Sustained and improved guselkumab response in patients with active psoriatic arthritis regardless of baseline demographic and disease characteristics: pooled results through week 52 of two phase III, randomised, placebo-controlled studies. RMD Open. 2022;8(1). doi: 10.1136/rmdopen-2022-002195. PubMed PMID: 35296534; PMCID: PMC8928386. FULL TEXT
Risk M, Hayek SS, Schiopu E, Yuan L, Shen C, Shi X, Freed G, Zhao L. COVID-19 vaccine effectiveness against omicron (B.1.1.529) variant infection and hospitalisation in patients taking immunosuppressive medications: a retrospective cohort study. Lancet Rheumatol. 2022;4(11):e775-e84. Epub 20220816. doi: 10.1016/S2665-9913(22)00216-8. PubMed PMID: 35991760; PMCID: PMC9381025. FULL TEXT

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