William Caldwell


William Caldwell


Academic Appointment(s)

Medical College of Georgia
Department of Pharmacology and Toxicology

Medical College of Georgia
Department of Culver Vision Discovery Inst

Emeritus Faculty


Retired as Professor and Chair of the Department of Pharmacology and Toxicology.
Rehired as Professor. Maintains an active, funded research laboratory and participates in the education of graduate and medical students.

  • (706) 721-3383
  • (706) 721-2347
  • CB 3622


  • Ph.D., Pharmacology. Emory University, 1969

  • BS, Applied Biology Georgia Institute of Technolog, 1965

Courses Taught Most Recent Academic Year

  • PHRM 5015

    Critical Care Pharmacotherapy
  • OPTH 5002

    Ophthalmology Rsch Elect
  • PHRM 8043

    Pharmacology & Therapeutics II
  • PHRM 9020

    Seminar in Pharmacology
  • PHRM 8042

    Pharmacology & Therapeutics I

Teaching Interests

Cardiovascular pharmacology and physiology


Selected Recent Publications

  • Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma., 2015
    Journal Article, Academic Journal
  • Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia., 2015
    Journal Article, Academic Journal
  • Correction: angiotensin II-induced arterial thickening, fibrosis and stiffening involves elevated arginase function., 2015
  • Activation of the endothelin system mediates pathological angiogenesis during ischemic retinopathy, 2014
    Journal Article, Academic Journal
  • Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism, 2014
    Journal Article, Academic Journal

Research Interests

Role of L-arginine availability in reactive oxygen species formation, immune cell function and vascular and retinal dysfunction in models of diabetes and diet-induced obesity. Role of arginase in metabolic and vascular dysfunctions related to diabetes and obesity