Theodore Johnson
Professor
Academic Appointment(s)
Medical College of Georgia
Department of Pediatrics: Hematology/Oncology
Medical College of Georgia
Department of Georgia Cancer Center
Medical College of Georgia
Department of Neuroscience and Regenerative Medicine
Administration
Department of The Graduate School
- THJOHNSON@augusta.edu
- (706) 721-4962
- (706) 721-3925
- CN 4142
Education
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MD, Medicine
Medical College of Georgia, 2004
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Ph.D., Molecular Medicine.
Augusta University, 2004
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BS, Chemistry, General
Georgia Institute of Technolog, 1997
Certifications
Awards & Honors
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Recognition of “a critical advance in the field of neuroscience” and invitation to give an encore presentation
American Academy of Neurology (AAN) Science Committee, AAN 2023 Annual Meeting, Platform presentation, 2023
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Exemplary Teaching Award
MCG, 2021
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Exemplary Teaching Award
MCG, 2017
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Outstanding Young Clinical Science Faculty Award
Medical College of Georgia, Faculty Senate , 2014
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Champion Award
University System of Georgia, MD/PhD Program, 2012
Courses Taught Most Recent Academic Year
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PEDS 5000
Basic Clkshp in PEDS
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PEDS 5009
Pediatric Sub-I
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RPED 5002
Pediatrics General
Teaching Interests
I teach medical students and resident physicians in the art and science of pediatric hematology and oncology.
Scholarship
Selected Recent Publications
- Indoximod-based chemo-immunotherapy for pediatric brain tumors: a first-in-children phase 1 trial, 2024
Journal Article, Academic Journal
- Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity, 2021
Journal Article, Professional Journal
- Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis, 2014
Journal Article, Academic Journal
- Host indoleamine 2,3-dioxygenase: Contribution to systemic acquired tumor tolerance, 2012
Journal Article, Academic Journal
- Modulation of tumor tolerance in primary central nervous system malignancies, 2012
Journal Article, Academic Journal
Research Interests
I am a physician-scientist and pediatric oncologist, concentrating on developing multi-modal chemo-immunotherapy for children with brain cancer. In my molecular immunology Ph.D. training, I was part of the research team that first reported the groundbreaking discovery of the immune-suppressive potential of indoleamine 2,3-dioxygenase (IDO) in human cancer, and the team that developed indoximod, a small-molecule inhibitor of the IDO pathway used in this proposal. I am the co-founder and Co-Director of the Pediatric Immunotherapy Program at Augusta University, where I oversee clinical trial operations.