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Betty Pace

Tedesco Distinguished Chair in Pediatric Hematolog

Betty Pace

Tedesco Distinguished Chair in Pediatric Hematolog

Professor

Academic Appointment(s)

Medical College of Georgia
Department of Pediatrics: Hematology/Oncology

Medical College of Georgia
Department of Georgia Cancer Center

Medical College of Georgia
Department of Biochemistry and Molecular Biology

Administration
Department of The Graduate School

Bio

I am a Professor in the Department of Pediatrics, and the Francis J. Tedesco Distinguished Chair of Pediatric Hematology/Oncology at the Medical College of Georgia, Augusta University.

  • BPACE@augusta.edu
  • (706) 721-6893
  • CN4112

Education

  • MD, Medicine Medical College of Wisconsin, 1981

  • BS, Math Marquette University, 1976

Certifications

  • PHY Ga Comp Med Brd, 2010

Awards & Honors

  • GRU Faculty Senate Basic Science Faculty Award 2013

  • Lifetime Diversity Champion Award University of Texas at Dallas, 2010

Teaching Interests

I enjoy teaching and training medical students, residents and junior faculty. My most active area is mentoring the next generation of physician-scientist to conduct bench research. I also teach graduate students about hematopoiesis.

Scholarship

Selected Recent Publications

  • Exploring epigenetic and micro RNA approaches for y-globin gene regulation Exp biol Med(Maywood), 2021
    Journal Article, Professional Journal
  • Novel histone deacetylase inhibitor CT-101 induces y-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects Blood Cells Mol Dis, 2021
    Journal Article, Professional Journal
  • Benserazide racemate and enantiomers induce fetal globin gene expression vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease Blood Cells Mol Dis, 2021
    Journal Article, Professional Journal
  • Benserazaide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease. Blood Cells Mol Dis, 2021
    Journal Article, Professional Journal
  • Streptococcus pneumoniae and its virulence factors H2O2 and pneumolysin are potent mediators of the acute chest syndrome in sickle cell disease Toxins (Basel), 2021
    Journal Article, Professional Journal

Research Interests

For the last 40 years as a physician scientist in pediatric hematology-oncology, I have conducted research related to drug development for sickle cell disease and provided clinical care up until 2023. My lab has provided to clinical collaborators preclinic evidence of drug efficacy for several agents such as HPPD, dimethyl fumarate, AN-233 and panobinostat among others, using the Townes sickle cell disease and beta-YAC mouse models. We are currently conducing a phase 1 clinical trial with panobinostat. I also have used my lab and mentoring skills to train over 100 students and residents and mentored over 114 junior faculty across the United States to conduct research related to blood disorders.