Paceline and MCG Foundation advancing innovative cancer research
Since 2019, 26 community-funded innovative cancer research projects at the Georgia Cancer Center have been made possible through Paceline grants.
The overall goals of the Molecular Oncology research program are to understand the fundamental cellular and molecular processes that contribute to cancer development and progression.
Normal cells have intricate molecular mechanisms that control essential phenotypes such as differentiation, cell division and movement. The molecular pathways that control these phenotypes are disrupted in cancer cells as a result of the expression of oncogenes and loss of regulatory tumor suppressor genes. These events, which are often highly specific to individual types of cancer, disrupt specific molecular pathways that result in uncontrolled cell growth and loss of normal responses to extracellular signaling cues that result in tumor development and progression.
The research interests of the program can be divided into three broad themes:
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Since 2019, 26 community-funded innovative cancer research projects at the Georgia Cancer Center have been made possible through Paceline grants.
“It is a great opportunity because we have a lot of great colleagues and great support in terms of core facilities and staff,” says Ahmed Chadli, PhD.
The grant awarded for Chadli’s research focuses on a specific protein, UNC45A, that can be used as a promising novel immunotherapeutic target in treating triple-negative breast cancer (TNBC).
This summer, high school students participated in the Georgia Cancer Center's first Summer Research Experience Program.