Integrated Genomics
The Integrated Genomics Shared Resource at the Georgia Cancer Center provides state-of-the-art technologies for DNA and RNA sequencing as well as spatial transcriptomics.
We offer a comprehensive suite of services, including sample processing for fresh, frozen, and fixed cells or tissues, library preparation, and next-generation sequencing (NGS) for both bulk DNA/RNA sequencing and single-cell/nuclei sequencing. For single-cell studies, we utilize the Chromium X system from 10X Genomics. Our sequencing platforms, the Illumina NovaSeq 6000 and NextSeq 500, enable high-throughput, efficient sequencing for a wide range of applications.
We have introduced single-cell spatial transcriptomics using the CosMx SMI platform, providing investigators with the ability to analyze single cells within their native tissue microenvironment. Additionally, we support spatial transcriptomics with the CytAssist instrument from 10X Genomics for Visium spatial profiling.
For nucleic acid and protein extraction, we utilize the QIAconnect system from Qiagen, ensuring high-quality sample preparation for downstream analyses.
Research Resource Identifier
To better track our publication history and ensure proper recognition, the Integrated Genomics Core has registered for a Research Resource Identifier (RRID) through RRID Portal.
RRIDs are unique identifiers assigned to research tools, core facilities, model organisms, antibodies, and other scientific resources. Including an RRID in publications enhances transparency, reproducibility, and proper attribution, helping to track resource usage and increase visibility within the scientific community.
Researchers using the core are asked to include an acknowledgment statement in their manuscripts. If core members have provided significant scientific contributions, they should also be considered for co-authorship.
Please modify this acknowledgment statement as needed but ensure the RRID is included:
"We acknowledge the support and contribution of the Integrated Genomics Core Shared Resources at the Georgia Cancer Center, Augusta University (RRID: SCR_026483)."
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Services & Additional Information
All services will be scheduled with the Core and billed through iLab
Integrated Genomics Core iLabServices & PricingResources Users
What We Offer
DNA Sequencing (inquire for more information)
Chip-Seq & Whole Transcriptome Seq
miRNA (inquire for more information)
RNA-SeQ High & Low Input
For high input RNA we can work with a minim of 300ng of RNA & for the low input we can work with a minimum of 25pg or 100 to 1000cell skipping RNA isolation.
Sample Purification
We house a QIAcube Connect instrument, a fully automated system designed for the purification of nucleic acids and proteins in molecular biology applications. This advanced system streamlines sample processing, ensuring high-quality, reproducible results with minimal hands-on time.
Engineered for professional users trained in molecular biology techniques, the QIAcube Connect automates workflows, enhancing efficiency and reducing variability.
Spatial Transcriptomic
Single Cell
The Chromium X Series instrument enables seamless scaling from pilot experiments through million-cell studies, and offers compatibility with an expanding range of Chromium Single Cell applications. This includes Single Cell Gene Expression Flex kits, which enable the most sensitive whole transcriptome profiling of fresh, frozen, and FFPE samples.
Trainings (inquire for more information)
Quality Control Analysis
Contact
Natalya Resto-Trujillo
- Research Associate | CN 3156E/F, 3162
- Part-Time
Diego Fernandez
- Data Analyst
- Part-Time